ABSTRACT
Introduction and Aim: The COVID-19 pandemic has caused a huge economic burden and impacted physical and mental health of the people. The young medical graduates are facing a lot of disappointments with regard to career, higher studies, personal life etc. The current research aims to assess the various stressors and their coping strategies among the young medical graduates during the COVID-19 pandemic. Material(s) and Method(s): The cross-sectional study was conducted in the Department of General Medicine at a tertiary care teaching hospital in South India. Undergraduate medical students of 228 in number of both genders who completed their residency training just before and during the COVID-19 pandemic were enrolled in the study. The data was collected through a preformed questionnaire. Ethics clearance was obtained from the Institutional Ethics Committee. Informed consent was obtained. Statistical analysis was done by SPSS software version 18.0. P value < 0.05 was considered statically significant. Result(s): The mean scores obtained in PSS-10 were found to be higher among males than females. Around 79.4% showed moderate stress while 20.6% showed high stress (P=0.001). Males showed more stress compared to females in general as well as academic stressors. Male doctors and female doctors had differing stress coping skills. Conclusion(s): The study highlighted the vulnerable state of mind of the young medical doctors. The best way to overcome stress is by providing adequate resources, training to cope stress and ambient conditions for study and work, social support and relaxation techniques at both individual and organisational levels to help them to achieve a reasonable work-family interface.Copyright © 2023, Indian Association of Biomedical Scientists. All rights reserved.
ABSTRACT
Background: Coronavirus Disease-19 (COVID-19) has a global impact. The laboratory assessments in Covid-19 illness help in better understanding the disease pathophysiology useful in screening asymptomatic individuals to diagnosis, prognosis and monitoring the affected patients. The aim of the study: To observe the association between biochemical and inflammatory parameters among the hospitalised COVID-19 patients of different clinical severity. Materials and methods: This was a retrospective study carried out with the approval of the Institutional Ethics Committee. The study included patients over 18 years, hospitalised with COVID-19 infection, grouped into three severity groups, admitted to ward, high dependency unit or intensive care unit between May to September 2020. Data collection was carried out by manual perusal of inpatient case sheets, computerised patient data system and transcription database for discharge summaries. The biochemical and inflammatory markers like plasma glucose, renal function tests, serum electrolytes, liver function tests, erythrocyte sedimentation rate (ESR), C-Reactive protein (CRP), d-dimer, ferritin, Lactate dehydrogenase (LDH) at the time of admission were collected. Data was expressed as mean and standard deviation or median and range. ANOVA test followed by post hoc (Tukey) test, Pearson correlation and Receiver Operating Characteristics (ROC) Curve analysis were performed. Results: Significant correlations were observed between the mild and moderate-severe illness groups with respect to fasting plasma glucose, blood urea nitrogen, creatinine, direct bilirubin, total protein, albumin, ferritin and LDH. The AUC was the highest for LDH at 0.64 followed by blood urea nitrogen to creatinine ratio at 0.62. Conclusion: High levels of renal function parameters were potential predictors of acute kidney injury among patients with COVID-19. Fasting plasma glucose, serum albumin, LDH, Blood urea nitrogen (BUN) and BUN-creatinine ratio are better indicators of the severity of the disease with multiorgan dysfunction. © 2022 Belgorod State National Research University. All Rights Reserved.